Tuesday, March 25, 2008

Intestinal Dysbiosis

Via Henry Bauer: an alternative theory to explain classic AIDS (as opposed to the more widely-defined HIV/AIDS of today), intestinal dysbiosis.

One thing that those who reject the HIV/AIDS hypothesis agree on is that HIV is not the cause of AIDS. But when it comes to alternative theories of causation, disagreement abounds. And some of the most vexing questions surround the earliest cases of AIDS, those that were initially dubbed Gay-Related Immune Deficiency (GRID). Why did it originate in some gay communities? Why did this happen in the late 1970s and early 1980s? Why in the particular form of PCP (Pneumocystis carinii pneumonia), candidiasis, KS (Kaposi’s sarcoma)? And why still do gay men so often test “HIV+”? Why do some “HIV+” people thrive without medication while others get ill?
Here’s a suggestion that answers all those questions in a coherent way. [...]
Inadvertent alteration of these intestinal microflora may eliminate beneficial bacteria while simultaneously promoting the proliferation of harmful microbes. This state, intestinal dysbiosis, can lead to a series of problems, problems which taken together may explain much of what is called AIDS, at least with respect to some groups of gay men.
First, the lining of the gut may become more porous than normal, a condition known as increased intestinal permeability or leaky gut (2). This then allows microbial translocation—a flood of antigens into the blood stream—to occur, which in turn sets off a systemic immune response and the production of large numbers of antibodies to lots of different things. This condition, hypergammaglobulinemia—too many antibodies to too many things—is a known cause of false-positive reactions on the “HIV tests”.


PlagueBlog recommends not delving too deep (i.e., more than three pages) into the PDF if you're squeamish. This is not a pretty theory, and that may be its main disadvantage in the marketplace of ideas.

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