Tuesday, May 23, 2006

The Family Cluster Expands

The World Health Organization reports that a seventh case, and sixth fatality, has been added to the family cluster of avian influenza in North Sumatra, Indonesia. The evidence points toward person-to-person transmission. On the bright side:

Full genetic sequencing of two viruses isolated from cases in this cluster has been completed by WHO H5 reference laboratories in Hong Kong and the USA. Sequencing of all eight gene segments found no evidence of genetic reassortment with human or pig influenza viruses and no evidence of significant mutations. The viruses showed no mutations associated with resistance to the neuraminidase inhibitors, including oseltamivir (Tamiflu).

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