Day 1090: Not the Vaxx, and Yet, Still the Vaxx

Although it's harsh on Scott Adams week in the Covidsphere, we'll leave that work to the bad cat (representing the "fear is the mind killer" camp) and Mathew Crawford (representing the "controlled opposition" camp).

Instead we'll flash back to last year's news about IgG4: "Class switch towards non-inflammatory, spike-specific IgG4 antibodies after repeated SARS-CoV-2 mRNA vaccination" in Science Immunology, followed in January by a similar result in Frontiers in Immunology: "mRNA vaccines against SARS-CoV-2 induce comparably low long-term IgG Fc galactosylation and sialylation levels but increasing long-term IgG4 responses compared to an adenovirus-based vaccine". (The first paper was preprinted in July, and the second submitted in August of last year.)

The bad cat and Alex Berenson go into some detail about the papers, but the short horror story is that the antibody response you get with repeated mRNA shots is akin to the one you get for allergens, and is not particularly useful against COVID qua infectious disease. This means that boosters not only make it more likely you'll catch COVID, but also make it more likely you'll die of COVID. So the vaxx is not necessarily killing people with the weird side-effects of an insufficiently-tested technology that has never succeeded before; it may just be killing them with...COVID.

PlagueBlog recommends avoiding drugs that have only been tested in a handful of mice, especially if said mice have only passed a vague and possibly harmful endpoint like "antibody levels".