Day 963: ADE in Vitro

The usual suspects have all picked up on the new report in Nature on antibody-depenent enhancement (ADE) from both COVID vaccines and monoclonal antibody treatments. To the pro-vaxxer cries of "this is merely in vitro," Eugyppius adds a handy reminder that we may already have plenty of in vivo data:

Remember how everywhere mass vaccination occurs, we tend to see higher frequencies of infection? Remember how, in the deeply unadjusted and unreliable UKHSA vaccine efficacy statistics from the start of the year, the double-vaccinated appeared to experience higher rates of infection and death than the unvaccinated? Crazy conspiracy theorists might be forgiven for wondering if these are the effects of antibody-enhanced virus replication in the lungs of people more than six months out from their second jab.