Record Marburg Outbreak

The WHO reports 132 cases of Marburg virus in Angola (127 of them fatal) breaking the previous record outbreak in the Congo. As this is an extremely high death rate (96%) even for Marburg, it seems likely that some survivors are going unrecorded.

Marburg Outbreak Nears Record Death Toll

Approximately 121 persons have died of Marburg virus in Angola since the current outbreak began, rivaling the record outbreak in the Congo between 1998 and 2000, in which 123 people died. A Portuguese national is currently hospitalized in Luanda and another died in Portugal on Saturday, soon after returning from Angola.

Marburg Virus Confirmed in Angola

Reuters reports that the mysterious Angolan hemorrhagic fever has been confirmed to be Marburg virus, a relative of Ebola.

Angola's Mystery Hemorrhagic Fever

Ebola has been ruled out as the hemorrhagic fever that has killed at least 77 people in Northern Angola since first appearing in November. A post on the ProMED-mail list suggested plague, but the geography of the outbreak makes plague spread from the Congo unlikely. Some reports claim that the victims have mainly been children under 5.

Consumption consumption

The New York City Department of Health and Mental Hygiene warns against consumption of some Mexican cheeses--namely, those contaminated with Mycobacterium bovis (bovine tuberculosis), which can cause illness and (rarely) death in humans.

The Health Department has identified 35 cases of tuberculosis caused by M. bovis in city residents between 2001 and 2004. In one of those cases, a 15-month-old child who died in March 2004 was later determined to have died from complications due to M. bovis infection.

Anthrax Scares

The CDC has the latest on recent anthrax incidents.

On March 10th, routine samples from an air sampling device at the Pentagon Remote Delivery Facility were collected and preliminary tests, reported to the Department of Defense (DoD) on March 14, indicated the possibility of the presence of Bacillus anthracis. Also, on March 14th, an alarm at a separate Defense office in the Skyline complex indicated the possibility of the presence of a biohazard. As a result, employees in close proximity to the mail handling at these two facilities and the United States Postal Service (USPS) V-Street feeder facility were placed on a 3-day course of prophylactic antibiotics.

Unidentified Hemorrhagic Fever in Angola

Via ProMED-mail: Prensa Latina reports that at least 56 Angolans, including 2 nurses, have died of an as-yet-unidentified hemorrhagic fever:

A medical source from Huige hospital told journalists they have termed this illness gastric hemorrhage. It begins with fever symptoms for two days and then the patient begins to cough up blood, falls into a coma, and dies within four days, he explained.

Typhoid Tran

The AP reports that a second nurse is showing symptoms of bird flu after treating a bird-flu patient in Vietnam:

The 21-year-old man is at the center of a cluster of bird flu cases that include his 14-year-old sister and 80-year-old grandfather, who has the virus without showing any symptoms.

Reuters reports on other asymptomatic cases.

Flesh-Eating Disease in Flagstaff

Via ProMED-mail: the Arizona Republic reports on two related cases of necrotizing fasciitis:

A patient with flesh-eating bacterium spread the infection to a health care worker at Flagstaff Medical Center, leaving both people hospitalized in serious condition.
The state Department of Health Services has asked doctors at the hospital to monitor other workers for symptoms, even though they don't think it has spread.
The DHS said the Flagstaff case represents the first documented case in Arizona of invasive Group A streptococcus spreading from a patient to a health care worker.
Officials at the medical center don't know how the disease was spread.

A Growing Family

The New York Times reports on the discovery of two new retroviral members of the H.T.L.V. family, kissing cousins to HIV.

The viruses, found in rural Cameroon among people who hunt monkeys and other primates, were probably transmitted from the animals through blood from bites and scratches received in hunting, butchering and keeping the primates as pets, the scientists said at the 12th Annual Retrovirus Conference, which ended here on Friday.

Polio in Ethiopia

The ongoing African polio epidemic has reached Ethiopia, with one confirmed case and another suspected, Reuters reports.. It all started in Nigeria:

Africa's polio epidemic erupted after a 10-month halt in immunization in Kano where Muslim elders said the vaccines were part of a Western plot to spread HIV and infertility, according to WHO officials. Nigeria, Africa's most populous country, recorded 763 cases in 2004, accounting for 2/3 of the toll. It resumed immunization in July 2004.

Cryogenic Bacteria

The Environment News Service reports on frozen microbes: they weren't infectious, but bacteria unearthed from the Alaskan tundra five years ago came to life in the lab after 32,000 years at -4° Celsius. It's taken the past five years to prove that it's a new species.

Commenters at Slashdot note that bacteria have been revived after 25 million years.

Rabies Roundup

Just a few interesting rabies stories from ProMED-mail: two patients died of rabies transmitted by organ transplants in Germany, a hunter died of rabies in Siberia, and a woman was bitten by a rabid coyote right here in Massachusetts.

Bird Flu Warnings

The front-page story in the Boston Metro today was this AP report on the "very high threat" of a bird flu epidemic.

Julie L. Gerberding, head of the Centers for Disease Control and Prevention, said scientists expect a flu virus that has swept through chickens and other poultry in Asia to genetically change into a flu that can be transmitted from person to person.

Pneumonic Plague

Thanks to another unnamed source for the pneumonic plague link. I also heard about it at the plague panel at Boskone this weekend, but I haven't had a chance to blog it until now. The outbreak among diamond miners in the Congo has been going on since December, but the WHO has only recently gotten involved. According to the BBC article, there are at least 60 dead and 350 infected.

Don't Eat the Apes

Via ProMED-mail, of course: Study links Ebola outbreaks to animal carcasses.

Specifically, the researchers found that Ebola infections in wild animals such as gorillas, chimpanzees, and occasionally duikers (a diminutive antelope species), move across the human-wildlife divide through hunters taking either sick animals or carcasses for meat. Hunters can then spread the disease to families and hospital workers, creating the conditions for an epidemic in the process.

Mad Goat

I've gotten behind on reporting, but I did get a friendly tip on the mad goat [ProMED] last week.

Britain said on Tuesday [8 Feb 2005] that a goat confirmed as having the brain-wasting disease scrapie in 1990 may have had mad cow disease. [...]
In January 2005 mad cow disease, formally known as bovine spongiform encephalopathy (BSE), was found in a goat in France, the 1st time the brain-wasting affliction that ravaged European cattle herds and killed at least 100 people had been diagnosed in another animal.

Stuffed Plague

What's the perfect gift for the plague-blogger who has everything? Giant Microbes! Thanks to my personal Epidemic Santa for the Black Death and company.

The Bard and the Pox

Steve Baragona of the Infectious Diseases Society of America argues against a recent article in Did Shakespeare have Syphilis?

Quahogs vs. Botulin

The Associated Press reports that quahogs are surprisingly resistant to botulism:

Researchers who injected the clams with enough botulism toxin to kill 1,000 people found the shellfish somehow neutralized the enzyme, which is considered a potential bioterror agent.