Tuesday, March 31, 2020

Day 60: Even the Queen

PlagueBlog is saddened to report the death of the Spanish Royal Princess Maria Teresa de Borbón-Parma, aged 86. Having started on FaceBook, the news took some time to reach us.

USA Today reported yesterday that the Federal Reserve Bank of St. Louis is projecting an unemployment rate of 32.1% for the second quarter. Bodies are piling up at morgues in Iraq due to fears about burying them. Japan is planning to extend its entry ban to countries including China, South Korea, the US, the UK, and most of Europe.

On the mask front, CNN reports that the WHO has dug in in their recommendation against masks. People don't seem to be listening, though; more of the unqualified masses in the streets (and more specifically, the supermarkets) seem to wearing them every day.

Rhode Island was apparently not the first spicy island state to declare open season on tourists. El Pais reports that police in the Andaman and Nicobar Islands, an Indian territory, ejected at least thirty foreign tourists at gunpoint earlier this month, shipping them all to the airport on the main island where they were forced to buy plane tickets to the mainland (while being sprayed with window cleaner). The tourists now appear to be holed up in an abandoned embassy building in Chennai, because the locals there beat one of them up when he emerged.

The New York Times reports on a super-spreading event in Georgia similar to our ill-thought-out Biogen conference. Reuters reports on a super-spreading event in France that puts all of ours to shame:
The prayer meeting kicked off the biggest cluster of COVID-19 in France - one of northern Europe’s hardest-hit countries - to date, local government said. Around 2,500 confirmed cases have been linked to it. Worshippers at the church have unwittingly taken the disease caused by the virus home to the West African state of Burkina Faso, to the Mediterranean island of Corsica, to Guyana in Latin America, to Switzerland, to a French nuclear power plant, and into the workshops of one of Europe’s biggest automakers.
And last but never least, the plague ships: Tasmania's second death is directly linked to Germ Boat #13, the Ruby Princess. According to The Guardian, the ill-fated (and ill-docked) cruise ship transported 440 cases to Sydney, which represents 10% of Australia's total case count, and 5 of its 19 deaths.
In a move the NSW health minister later admitted was a mistake, 2,700 passengers were allowed to disembark without checks from NSW Health on 19 March, with many boarding flights interstate. Another boatload of passengers did the same on 8 March.
Since we're on the topic, DutchNews reports a Dutch national was the fourth to die aboard Germ Boat #18, the MS Zaandam (Holland America), which has been at sea for a two-week tour out of Buenos Aires since March 7th. Eight people have tested positive but about 200 are showing symptoms. After the Zaandam was refused docking at its original destination in Chile as well as in other South American nations, it spent some time anchored off Panama, where it transferred some healthy passengers to Germ Boat #19, the MS Rotterdam (so designated because, despite being apparently uninfected, it is as much of a pariah as #18 and is now also its travelling companion).

Panama reversed its initial decision and let both ships through the canal "for humanitarian reasons" on Sunday. The plague ships are now chugging towards Florida, though the governor has expressed his disinterest in allowing foreigners to be "dumped" in his state.

P.S. The Hill reports that the CDC may buck the WHO and encourage Americans to wear masks.

P.P.S. Today's Massachusetts numbers are up 868 (15%) to 6620. There were 33 more deaths, though, for a total of 89. Deaths are now broken out by decade (only one was under 60), county, hospitalization status, and pre-existing conditions (yes or no). Quest performed another 2,200 tests while the state did 20 (and also somehow went down one positive over yesterday). Suffolk County has pulled ahead of Middlesex again.

It's unclear how many of today's seven deaths in Hampden County are due to the "stunning breakdown of public health protocol" at the Holyoke Soldiers Home; the Boston Globe reports a death count of 13 with 17 cases among living residents and staff and more tests pending.
[Health and Human Services Secretary Mary Lou] Sudders said state officials are still trying to confirm important details, including precisely when the residents died, when they were tested for COVID-19, and who in their families were informed. She said the deaths were not reported to state officials.

Monday, March 30, 2020

Day 59: Mask Madness

Bolsonaro continues to keep Brazil open for business, saying "We're all going to die one day." (Todos nós vamos morrer um dia.)

Business is a little different in the Czech Republic, where Aktuálně.cz reports that 680,000 masks and 28,000 respirators were seized by the government after a local company attempted to sell them to the Ministry of Health at inflated prices. The reseller obtained the masks from one Zhou Lingjian, a man allegedly "directly linked" to the government of Communist China. All PPE was seized from his warehouse, including (allegedly) some intended as humanitarian aid for Italy. How the supplies stopped in Czechia instead remains unexplained, as the border was open for such shipments the whole time. The Czech police suspect theft.

Austria will be requiring people to wear masks in grocery stores starting Wednesday (free at the door), and recommends wearing them elsewhere. The FDA has approved using an Ohio company's mask sterilization technology at full capacity (80,000 masks a day), apparently in response to the governor's criticism of their initial arbitrary restriction to 10,000 a day.

The US has reached 164,000 cases, and Italy is now over 101,000. New York at 67,000 cases is ahead of Germany (66,000). Massachusetts has sadly risen in the rankings lately and is now at 5th in the nation with 5,752 cases (up 797 or 16% from yesterday). Eight new deaths, including several of people in their 60's, brings us up to 56 deaths.

Reddit reports that your Android phone will now warn you when you cross the state line into RI, where it's still tourist hunting season. PlagueBlog recommends turning off this feature if you live on the state line.

Sunday, March 29, 2020

Day 58: Ash Lines and Riots

Today's numbers are down; Sunday seems to be the state lab's day of rest, and we'll surely get another Monday leap. Massachusetts now has 4955 cases, up 698 (16%) from yesterday, with 4 new deaths (all of persons over 70). Middlesex has retaken the lead with 981 cases as opposed to Suffolk County's 940. Essex has pulled ahead of Norfolk, 570–548. Quest tested 2,000 more people, while the state lab tested 2.

In Maryland, a man was arrested for inadequate social distancing outdoors. People seem to be smuggling video out of New York hospitals to the New York Times. If you want to know when your state will reach Peak New York, the Institute for Health Metrics and Evaluation at the University of Washington has projections for peak hospital demand (including how many hospital and ICU beds your state actually has). Just select your state from the dropdown to read 'em and weep.

There's also a new kid on the case-counting block, covidly.com, which makes nice graphs but doesn't seem to be updating in real time. Over on worldometers, the pandemic has already hit 718,000 cases with well over 33,000 deaths. Italy is nearing 100,000 cases. Spain is close to pulling ahead of China in cases, and is second only to Italy in deaths, if you believe China's numbers.

PlagueBlog's faith in China's numbers, if it existed at all, would be shaken from news out of Wuhan of thousands of people queueing up at funeral homes for urns of their relative's ashes. Urn counts have been estimated at 45,000, far in excess of the nation's official death toll of 3,300. Pictures and video of the ash lines posted to social media have been censored.

The Sun also reported rioting when residents of Hubei discovered their quarantine wasn't as over as they thought it was: they're still not allowed to travel around China.

P.S. After Cuomo threatened to sue, Rhode Island extended tourist hunting season to all out-of-staters. Those Massachusetts folks with houses straddling the state line should exercise caution when entering their living rooms.

Saturday, March 28, 2020

Day 57: Turkey Sightings

With the world at 663,000 cases and 30,000 deaths, the US is firming up our grip on the lead with over 123,000 cases and over 2,000 deaths. Only Italy has also surpassed China, with 92,000 cases and 10,000 deaths (despite undercounting their deaths).

Today's count for Massachusetts is 4257, up 1017 (31%) from yesterday. In a surprise upset, Suffolk County has surged ahead of Middlesex County by one case (843-842). There have been 9 more deaths, for a total of 44. Quest is up another 3,000 tests to over 17,000, which is almost half the tests ever done in the state.

We have not taken to hunting down New Yorkers like the neighbors yet, though we are quarantining visitors to the state. (Presumably Rhode Islanders with homes straddling the state line can travel to the kitchen and back without being quarantined, but they should not hunt New Yorkers while they're here in Massachusetts. Apparently people in distant places like New York disapprove.) Instead, the new sport here is turkey-spotting. They've been seen all over the Boston area, including at the Anna's in Brookline.

In other local news, New Balance is ramping up to produce masks, and the Public Health Commissioner has COVID-19 and so is working from home. Partners hospitals are banning visitors, and a Scituate animal shelter has set up a pet food food pantry.

Friday, March 27, 2020

Day 56: The Herd Strikes Back

Today's title is for Boris Johnson, currently self-quarantining at Number 10 Downing Street.

Do you recall when PlagueBlog did not recommend closing the border to New York State? Well, clearly the governor of Rhode Island is not listening to our recommendations, because she has instituted a house-to-house search for roving New Yorkers, using the National Guard. (This somehow reminds PlagueBlog of the popular theme in Portuguese COVID-19 memes of reconquering a disease-ravaged Spain, or at least Galicia.)

Science Alert suggests that the current coronavirus may be a chimera of a bat coronavirus and a pangolin one.
RaTG13, isolated from a bat of the species Rhinolophus affinis collected in China's Yunan Province, has recently been described as very similar to SARS-CoV-2, with genome sequences identical to 96 percent.

[...]

However, the coronavirus isolated from pangolin is similar at 99 percent in a specific region of the S protein, which corresponds to the 74 amino acids involved in the ACE (Angiotensin Converting Enzyme 2) receptor binding domain, the one that allows the virus to enter human cells to infect them.

By contrast, the virus RaTG13 isolated from bat R. affinis is highly divergent in this specific region (only 77 percent of similarity). This means that the coronavirus isolated from pangolin is capable of entering human cells whereas the one isolated from bat R. affinis is not.

In addition, these genomic comparisons suggest that the SARS-Cov-2 virus is the result of a recombination between two different viruses, one close to RaTG13 and the other closer to the pangolin virus. In other words, it is a chimera between two pre-existing viruses.
P.S. Our numbers are in: Massachusetts is at 3240 cases, up 823 (34%) over yesterday. There were ten more deaths, mostly of patients over 80, for a total of 35. Sex is a growing mystery to the DPH, as is the source of the infection, with over 800 more in the "under investigation" category. Quest has tested 2,800 more patients, more than three times the next runner up (the state lab). A total of seventeen labs (plus "other") are now performing tests.

The commonwealth has officially extended the tax filing deadline to July 15th, and the Governor is on the case of cities who've banned construction.

Also the US has now topped 100,000 cases and 1,500 deaths. New York State is far in the lead with 44,800 cases and 519 deaths.

Thursday, March 26, 2020

Day 55: 525,000 Strong

Today the world has exceeded 525,000 cases of the coronavirus we are uniquely not naming after where it came from (well, uniquely except for the other coronavirus from China), with over 23,000 deaths and over 123,000 recovered. With a new high of over 82,000 cases, the US has edged out China for most cases, though not for deaths. Despite underestimating deaths, Italy is still ahead of the viral superpowers with over 8,000 dead. Spain is moving up in the ranks, with second place in deaths and fourth place in cases.

Today's bad news in Massachusetts isn't as bad as yesterday: we are up 579 cases (32%) to 2417, with ten new deaths, mostly among 80-year-olds, for a total of 25. Middlesex still leads the counties; one notable case here is a Market Basket employee in Chelmsford. An Easton Shaw's employee of unknown residence also tested positive.

Failure to trace continues apace, with one more travel-related case, 17 more official local transmission, and over 500 more untraced cases, for a total of over 2000 under investigation. Strangely, a sex unknown category has appeared in the state statistics, with 2 cases. Quest has another 333 positives, out of 2,330 more tested. A fourteenth lab has appeared in the list (BROAD) but without numbers because it is not yet validated.

In the battle over hydroxychloroquine, the Detroit News reports that the governor of Michigan has taken the other side, forbidding doctors from prescribing it off-label. The article is too stupid to explain why, but the restriction is most likely related to a similar one in Ohio meant to guarantee access for patients needing the drug for its on-label purpose (fighting autoimmune disease).

Wednesday, March 25, 2020

Day 54: Diana's Revenge

Basically everyone on the internet has informed PlagueBlog that Prince Charles has come down with coronavirus, so we're passing it on to you. Take it as you will.

Here in Massachusetts, things have gone from bad to worse, or at least from untested to tested. The total is now 1838 cases, up 679 from yesterday (59%). We also have 4 new deaths, all over 70 and most with pre-existing conditions. The jump is mostly due to testing by Quest, whose numbers have gone up from 379 positive out of over 5,000 tested yesterday to 805 positive out of over 9,000 tested today. The state comes in a distant second with 4,774 tested. LabCorp remains in third place, and the lab count is up to thirteen, plus "other".

P.S. If you're on hydroxychloroquine, PlagueBlog hopes you're also a prepper and stocked up ahead of the rush. Buzzfeed reports Kaiser Permanente is denying hydroxychloroquine prescriptions to lupus patients in California. Also, PlagueBlog recommends against drinking your fish tank cleaner because you don't understand chemistry (or for any other reason).

Tuesday, March 24, 2020

Day 53: It's a Doozy

I was going to start out with Hong Kong's official report of a second pet case, detected earlier this week in a German Shepherd tested and quarantined on account of its sick owner, but the Massachusetts numbers are out for today and they're a bit much. We are up 382 cases (49%) to 1159, with two additional deaths. Middlesex County alone is over 300 cases, and Essex County is up-and-coming. There are 11 more travel cases, 16 more local transmissions, and an ever-growing backlog with the source under investigation. (Possibly included in the case count for today are the President of Harvard University and his wife; he emailed the community that he got their results back this morning.)

On the bright side, there's a full lab breakdown starting from yesterday, with 12 labs listed (plus, of course, an "other" category). Testing is up 54% over Sunday, with 13,749 tests performed. About 8% have been positive. Though there's been discussion of repeated testing of healthcare workers, this doesn't seem to be reflected in the table.

In case you didn't believe that was the bright side, CTV News reports that Spain has set up a temporary morgue on a Madrid ice rink, as well as field hospitals and military cleaning patrols.

Monday, March 23, 2020

Day 52: Anosmia Joins the Symptom List

Today the world exceeded 350,000 cases, 15,000 deaths, and 100,000 recoveries. Italy is eyeing 60,000 cases, which will be 0.1% of their total population. The US is at 35,000 cases and Spain, a nation of fewer than 47 million souls, is attempting to catch up to us with over 33,000 cases. Germany has pulled ahead of Iran despite their similar populations (around 80 million) and Iran's significant head start. France is falling behind.

In Massachusetts, yesterday's mysterious Duke/Nantucket combined counties case has turned out to be on Nantucket, and the entire island is now sheltering in place. The governor discouraged people from traveling to the islands, then also discouraged the latest fad, traveling across the mainland in search of the ever-more-elusive haircut, by shutting down all non-essential services. FYI: Packies are essential, recreational marijuana dispensaries are not.

One of the more interesting symptoms to emerge from the pandemic is post-viral anosmia or hyposmia, most notably in otherwise asymptomatic patients. If you want to read a bunch of anecdotal reports of the loss of the sense of smell (and therefore of much of the sense of taste), see yesterday's Hacker News thread inspired by the ENT UK post. According to the anecdotal evidence, most people recover their senses eventually.

Also on the science front, last week Cell Discovery finally posted a letter about the efficacy of hydroxychloroquine (a milder form of everyone's favorite repurposed malaria drug, chloroquine) against coronavirus in vitro.

P.S. Today's numbers are in: Massachusetts is at 777 cases total (+131, or 20%), with no new deaths. There were seven more travel cases, 21 more cases of local transmission, and now almost 500 unsourced cases. My county (Middlesex) still leads the pack with 232 cases, well over Boston proper (Suffolk, 154) or anywhere else. Dukes County (Martha's Vineyard) remains free of disease.

Locals should note that besides the state closing for non-essential business tomorrow, indoor gatherings are now limited to 10 persons. Outdoor gatherings are allowed, but I saw a lot of parks padlocked today anyway.

P.P.S. The death count for today is actually 9, up 4 over yesterday. PlagueBlog could swear the PDF said 5 this afternoon. Also, more news sources cannot count the counties of Massachusetts.

Sunday, March 22, 2020

Day 51: Next Stop, Italy

The US has reached 30,000 cases, putting us in a firm third place after Italy (53,000) and the source of it all, China (81,000). New York State alone has exceeded 15,000 cases (with 9,000 in New York City alone), leaving all the other states with their impaired testing capacities in the dust. PlagueBlog does not recommend closing the border with New York at this time.

On the plague ship front, The Patriot Ledger reports that hundreds of passengers aboard Germ Boat #15, the Silver Shadow, remain quarantined in the port of Recife (Brazil) after a single passenger tested positive. Despite promises of an airlift out for Americans this weekend, about a hundred remain aboard.

A sister ship, the Silver Explorer, earns Germ Boat #16 status by being in a similar situation off the port of Castro, Chile, after an 85-year old British man disembarked in the south and tested positive in Coyhaique. Silversea Cruises is a subsidiary of Royal Caribbean.

Chile has also refused docking to Germ Boat #17, the Azamara Pursuit, despite its having no verified cases aboard. Other South American ports have refused it entry, and it may need to make the entire 13-day sail back to Miami to offload its (for the moment) healthy passengers. Azamara Cruises is a wholly owned subsidiary of Royal Caribbean.

P.S. Massachusetts' numbers are out for today: 646 cases, up 121 (23%) from yesterday, with 5 deaths (+3). The commonwealth is now providing age ranges on the case numbers. The curve is fairly flat and may be an archive of the testing priorities. Two more cases have been attributed to the Biogen conference, fifteen to travel, fourteen to local transmission, and almost 400 remain unsourced at this time. Positive results are down to 11% for the state lab and up to 7% for the commercial labs.

For some reason the DPH lumped Dukes County and Nantucket County together (with 1 case total), misleading some news outlets into claiming that every county now has a case.

P.P.S. I corrected some number comparisons above.

Saturday, March 21, 2020

Day 50: And the Ship Sailed On

The worldwide case count has exceeded 309,000 with over 13,000 deaths. In Massachusetts, today's number is 525 cases, up 112 (27%) from yesterday, with 4 travel-related cases and the remainder due to community spread or not yet sourced. The biggest jumps are in the Greater Boston counties, along with noticeable increases in Essex, Bristol, and Plymouth counties. In a considerable number of cases the county is unknown.

Although not included in today's numbers, Channel 25 reports the death of a Middlesex County woman in her 50's with pre-existing conditions.

Some updates from yesterday: the death in Suffolk County was of an 87-year old Winthrop man. More disturbingly, Channel 25 reported that 9 health care workers at Brigham and Womens and 10 health care worker at Tufts Medical Center tested positive, far exceeding their actual case counts (though not the number of patients pending results at both hospitals). It's not clear how many days of testing this total represents. PlagueBlog is duly alarmed.

On the plague ship front, the numbers have changed yet again for Germ Boat #2, the Diamond Princess, with an eighth death today, a Canadian man in his 70's who had been hospitalized (apparently in Japan). Also some time last week, the Japanese suddenly counted fifteen more positives among ill passengers and their contacts who disembarked before the end of quarantine, bringing the total back up over 700 to 712. The New York Post reported Friday on a study determining that foodservice workers were the nexus of this particular germ boat outbreak.

The New York Times reports on yet another ill-omened cruise aboard Germ Boat #14, the Costa Luminosa. PlagueBlog was surprised by the Princess Cruise yesterday, but always suspected that Carnival Cruise Lines would go on operating its other cruise lines after announcing the apparently quite half-hearted closure of Princess. One of those lines is, of course, Costa Cruises.

The Costa Luminosa sailed out of Fort Lauderdale on February 24th for a Caribbean cruise on which its Italian passengers experienced some issues disembarking, though one Italian passenger was allowed to be hospitalized for an apparently unrelated condition. (He later died of coronavirus.) The ship sailed on out of Fort Lauderdale again, for Europe, reportedly only "half full". A second ill Italian was removed to hospital at a stop along the way. She also eventually tested positive. A comedy of errors ensued with no precautions being taken against the spread of the virus for a week, and then the homemade napkin masks appeared on the waiters.

The US would not permit the ship to dock at its original destination in Italy, so the plan was changed to Marseilles. Several other European ports of call turned the ship away. Yesterday, 400 American and Canadian passengers were finally airlifted home from Marseilles under "harrowing" conditions. Today the plague ship docked in Savona, Italy, despite the country being closed. Italian and Swiss passengers began to disembark; more will disembark tomorrow.

There is so much more news: more plague ships, more disturbing clusters across New England, and a run on chloroquine. PlagueBlog struggles to keep up while also working on a better view of the Massachusetts data.

Friday, March 20, 2020

Day 49: A Quarter Million Strong

Today the international case count has hit 255,000, with 10,000 deaths and almost 90,000 recovered. Italy has over 41,000 cases and 3,400 deaths. Spain has exceeded Iran in cases; both are nearing 20,000. Germany has well over 17,000 cases and the US is approaching 15,000, with 160 deaths.

Today the Treasury Secretary moved Tax Day to July 15th; filing and payment can be delayed without penalty. In a sudden move, Governor Newsom locked down the entire state of California late yesterday with a "shelter in place" order, though marijuana dispensaries and other "essential" businesses will remain open. Pennsylvania is also under a similar order. Massachusetts is still looking good, having dropped to 9th in the nation in case count with no deaths (unlike 28 states and the District of Columbia).

The Internet dug up this gem of a paper from 2007 [PDF]:
[SARS'] acute and dramatic impact on health care systems, economies, and societies of affected countries within just a few months of early 2003 was unparalleled since the last plague. The small reemergence of SARS in late 2003 after the resumption of the wildlife market in southern China and the recent discovery of a very similar virus in horseshoe bats, bat SARS-CoV, suggested that SARS can return if conditions are fit for the introduction, mutation, amplification, and transmission of this dangerous virus.
And lastly, the gift that keeps on giving: plague ships! Lucky Germ Boat #13 is the Ruby Princess, a Princess Cruises ship that (despite Carnival allegedly suspending operations of Princess Cruises a week ago) was still cruising around as late as yesterday when it docked in Sydney. Although thirteen people were ill with flu-like symptoms, the 2,700 passengers were allowed to disembark. Only the ill seem to have been tested; two passengers and one crew member tested positive. Another passenger who travelled to Tasmania has been hospitalized there and is a suspected case.

PlagueBlog trusts this germ boat will continue yielding cases for some time.

P.S. Forbes has an article on the homemade mask movement.

P.P.S Governor Cuomo tweeted his intention to lock down New York State.

P.P.P.S PlagueBlog apologizes for jinxing us: the governor reported the first death in Massachusetts during a press conference this afternoon. The victim was a Suffolk County man in his 80's with pre-existing conditions who died yesterday. The remaining numbers for today are not out yet.

P.P.P.P.S Our numbers are now out. Massachusetts has 413 cases, up 85 (26%) over yesterday, with 17 new cases of local transmission, 15 more travel-related cases, and the remainder under investigation. Middlesex County has 25 new cases, Suffolk 14, Norfolk 12, and Essex 10. Fifty of the new positives were found by the commercial and mystery labs. The state lab positive rate has gone down to 11% while the commercial lab rate has gone up to 5%. (There is still no denominator on the mystery labs.)

Thursday, March 19, 2020

Day 48: Lies, Damn Lies, and Statistics

The international case count has exceeded 222,000, with over 9,000 deaths and 84,500 recovered. Italy is approaching 36,000 cases and 3,000 deaths. Iran, Spain, and Germany remain in the teens, and the US, at nearly 9,500 cases and 157 deaths, is now on the wrong side of both France and South Korea.

Massachusetts has dropped to 8th in the nation in case counts. We still have no deaths, though 23 states have at least one already. Many Massachusetts grocery stores have implemented senior hours, and daycare centers will be shut down on Monday, except in certain circumstances involving essential workers.

The Sun Chronicle reports a hospitalized case in Attleboro from an unspecified nursing home, as well as the first case in Mansfield. As of yesterday, there were twelve cases in Southeastern Mass: five cases in Bristol County, five in Plymouth County, two in Barnstable County (the Cape), and none on the islands.

PlagueBlog recommends a New York Times opinion piece from Tuesday about the public health consequences of lying to the public about the need for face masks.

P.S. BBC News reports Italy's death toll has exceeded China's.

P.P.S. Our numbers are out for today: 328 cases total in Massachusetts, up 72 cases (including 4 in Southeastern Massachusetts), with 8 more cases of local transmission, 8 more travel-related, and 56 still under investigation. Hospitalizations went up from 27 to 43 (with a large number still unclassified).

The state lab found 37 of the new positives, the commercial labs (only LabCorp today) found 18, and the underspecified other labs found 17. Total test rates are still unavailable for the other labs, but the state and the commercial labs are still holding at 13% and 4% positive, respectively.

Wednesday, March 18, 2020

Day 47: 200k and Still Rising

In an overnight leap, worldwide coronavirus cases have passed 200,000 and reached somewhere between 203,529 (JHU CSSE) and 204,831 (WoM). Italy is over 31,000 cases with over 2,500 deaths. Iran also leapt up overnight to over 17,000 cases and over 1,100 deaths.

Also on the wrong side of South Korea are Spain (at almost 14,000 cases and over 600 dead) and Germany (over 10,000 cases but only 27 dead). Portugal (642 cases, 2 deaths) stopped trains and flights to Spain Monday night at 23:00, for at least a month.

The US is still on the right side of South Korea (though not for long) at about 7,300 cases and 116 deaths. New York has not been doing as well as Massachusetts; WoM reports 2,480 cases and 16 deaths for them. In fact, New Jersey has pushed Massachusetts into 5th place, and Florida is looking likely to overtake us soon as well. We are the only state with more than 100 cases but no deaths (out of 12).

New Hampshire is up 9 cases to 26. In Maine (32), Reddit reports that the L.L.Bean flagship store in Freeport is installing locks in preparation to lock its doors for the first time since it opened. Apparently they did close on some occasions; like Massachusetts and RI, Maine law requires retail stores to close on Thanksgiving. (PlagueBlog thinks the rest of you are animals.)

P.S. The Massachusetts numbers are out in their PDF hidey-hole. We have 38 new cases, -5 attributed to Biogen (so it's hard to say exactly where those five presumably misclassified folks went), 5 to community spread, 2 to travel, and 36 under investigation. The Commonwealth tested 377 new cases, 28 of whom were positive. The commercial labs tested 144 new cases, 10 of whom were positive. Their overall rates are now 13% and 4% respectively.

The Boston Globe reports that a swab shortage is now interfering with coronavirus testing. PlagueBlog hopes you got tested back when PlagueBlog recommended it.

Tuesday, March 17, 2020

Day 46: The Swiftness of Wind

Through the sneaky approach of guessing the URL, PlagueBlog brings you the Massachusetts numbers for St. Patrick's Day before 4:30pm today. We have 21 new cases, for a total of 218: 2 new Biogen cases, 6 new travel cases, 5 new local transmission cases, and 8 new mysteries. Quest has reported 5 new positives, while LabCorp has 116 new negatives and no new positives.

I've been noticing the difference between the state lab positive rate (17% yesterday, 14% today) and the commercial lab one (4% yesterday, 3% today). The LabCorp rate is particularly low at 0.6%. Unfortunately, without a breakdown of where the commercial tests are being done, it's difficult to speculate about why the commercial lab rates are quite so different from each other. The state lab's high rates clearly have to do with its restrictive testing requirements, especially before they were eased up last week.

Elsewhere on the continent, Brazil announced its first death, of a 62-year-old São Paulo man who also had hypertension, diabetes, and an irrelevant prostate condition which O Globo felt the need to explain. His travel history was not provided.

P.S. The South China Morning Post reports that the coronavirus-positive Pomeranian died Monday, after having never shown symptoms, testing negative, and being released from quarantine to return home Saturday. The late Pomeranian first tested positive nineteen days ago (on Day 27 of the Boston count).

The owner has refused an autopsy; not surprisingly, the government that destroyed previous research into the disease seems to also be allowing this vital dog data to be lost. PlagueBlog notes that human beings have also died after testing negative.

P.P.S. West Virginia has joined the club.

Monday, March 16, 2020

Day 45: Last Diner Before Summer

The Governor's crackdown on eating out begins tomorrow, so tonight is your last chance. Other states besides Massachusetts following Hoboken's lead include Connecticut, New York, New Jersey, California, Ohio, Illinois, Washington, Oregon, Maryland, Minnesota, Michigan (on very short notice), and 5 counties in Pennsylvania. Also the cities of Los Angeles, Washington DC, and Harris County, TX (i.e., Houston). Abroad, countries like Poland, Belgium, France, the Netherlands, Albania, Israel, and Czechia have closed restaurants.

Open Table reports things were looking pretty depressed for the industry already. PlagueBlog assumes the Open Table reservation numbers understate the situation, because you know you don't need a reservation these days.

The Boston Globe reports that unfortunate Worcester man who died on his way home Saturday has (posthumously) tested negative for COVID-19. The numbers for Massachusetts today are 197 total (+33 over yesterday), of which 100 have been connected to Biogen, 18 are travel-related, 28 are officially due to local transmission (apparently including the previous Western Mass cluster), and 51 are still under investigation. Of the positive tests, 8 are being excluded from further tabulation for being pre-March tests conducted by the CDC, 1 was done by LabCorp, 7 by Quest, and the remaining 181 were performed by the DPH.

Sunday, March 15, 2020

Day 44: Dubaious Death

The National reports that a 59-year-old Worcester man returning home to Logan from Chennai via Dubai died of cardiac arrest en route. The state police here are awaiting the autopsy and coronavirus test results—as are the 321 other passengers and 18 crew aboard the Boeing 777, especially the crew members who attempted CPR. The man had no pre-existing conditions but had been ill with gastrointestinal issues for an unspecified number of days before his flight. (Unlike "cold symptoms", gastrointestinal symptoms are an early sign of coronavirus infection.)

Here on the ground, the Commonwealth reported 164 cases total as of today, 108 traced to Biogen, 35 not yet traced to Biogen, 8 new travel-related cases, and no change in the Western Mass. cluster. PlagueBlog has heard that it's not clear to outsiders from the news that the Greater Boston area has pretty much shut down, with most school systems closed and many bars and restaurants now voluntarily closing. The mayor of Boston has also declared a health emergency, though it's not clear that means much at this point.

Rhode Island reached 20 cases yesterday, with no new cases today. Two recent cases are particularly notable, though: the Providence Journal reports that two children (age not specified) are among the cases. One had been on a cruise, and the other had gotten a signature from one of the two infected Utah Jazz players at their game in Boston on March 6th.

New Hampshire is up to 13 cases. The seventh case, a Rockland County woman, apparently worked at the Manchester DMV. If you visited the DMV in early March, you may want to read more about the case.

The New York Times reports that, due in part to union pressure, even the New York City school system will be closing starting Monday, until at least April 20th. The school system has 24 hours to figure out how to provide meals and childcare to some of the displaced students; remote education is to be planned out later this week. Public schools on Long Island and in Westchester County will also close.

NYC has now had five deaths, all involving pre-existing conditions, and the state has over 700 cases. The New York presidential primary may be delayed from late April until the date of a local election in late June. Louisiana and Georgia have also delayed their primaries.

Because, understandably, people just keep on drinking, the city of Hoboken (NJ) has closed all bars and restricted all restaurants to take-out only service, as well as implementing a 10pm curfew. The mayor excused all this in part with a confusing story about lack of EMS response to a bar fight on Saturday night.

Across the US there are 3,621 cases with 63 deaths, still mostly in Washington State and California. Italy is approaching 25,000 cases and Iran 14,000. Rumors about the UK "herd immunity" plan are greatly exaggerated. Hopefully the rumored vaccine from Israel (193 cases) is slightly less exaggerated. Austria, at 800 cases, has banned all gatherings of more than 5 persons.

P.S. The Governor of Massachusetts held a rare Sunday night presser to announce that our gatherings are now restricted to 25 people (down from 250), our restaurants are restricted to delivery and take-out only, and all schools, public and private, are closed for three weeks starting Tuesday. He closed some number of government offices, and the RMV (our DMV) is offering some extensions.

Visits to nursing homes are no longer allowed, hospital visitors must be screened, and non-essential procedures will be cancelled starting Wednesday. All commercial insurers are required to cover telehealth now, for free in the case of COVID-19, and some pharmacists will be allowed to make hand-sanitizer. (I suppose you used to have to be a compounding pharmacy to do so.)

The presser also claimed community spread in seven counties, even though we only have six counties with more than one case documented by the MDPH. It seems they've been peeking at the commercial lab results (seven of these have been positive already) and have decided some other cases won't be traced. Still, I think they may be exaggerating a bit to get people to hunker down before it's too Washington State.

He also mentioned the postponement of the Boston Marathon until September, news I'd missed earlier in the week. The Boston Globe article mentions that the MBTA will be running in full force Monday, but public transit service is likely to get reduced as soon as they come up with a plan to do so.

Saturday, March 14, 2020

Day 43: Just Get Tested

PlagueBlog has noticed that the mob microphone that is the Internet has not actually caught on to the fact that you can just get tested now in the US, by your own doctor, using the same labs (Quest and LabCorp) they use for every other test they give you, without any clearance, interference, or gate-keeping from your state, commonwealth, or the CDC. If your doctor refuses to test you, do not blame your state, commonwealth, or the CDC; blame the malfunctioning mob microphone.

The US is at over 2,800 cases and 57 deaths. Massachusetts is at 138 cases, 104 attributed to Biogen, 21 not yet attributed to Biogen, travel-related cases unchanged, and the Berkshire 8 unchanged except now somewhat anonymized as "Western MA cluster". (Nevertheless, the Boston public schools will be closed until April 27th.) New York State is at over 600 cases and two deaths, an 82-year-old woman in the city and a 65-year-old man in Rockland County. Connecticut has reached 11 cases.

Remember, you can just get tested.

Friday, March 13, 2020

Day 42: Fly Now or Forever Shelter in Place

Today's numbers (according to BNO) have exceeded 138,000 cases, 5,000 dead, and 70,000 recovered. Italy has exceeded 15,000 cases and 1,000 dead. Iran is over 11,000 cases and 500 dead. South Korea, the new social distancing capital of the world, has kept their numbers under 8,000 cases, with only 67 dead. Spain is over 4,200 with 120 deaths, while France and Germany are hovering around 3,000 cases.

The US is next up, with 1,832 cases and 41 deaths. (The new deaths appear to have occurred in Washington State, though the CDC hasn't recognized them yet.) No other countries have hit 1,000 yet besides China, whose new case counts have become negligible, though Switzerland and the Scandinavian countries are getting close.

Our World in Data is tracking doubling times, though they only have them listed for EOD Wednesday right now [updated since to Thursday, with cool new graphs], when the US and Spain were at 2 days and Denmark at 1 day to double the number of cases.

Portugal provides a handy map of cases, divided into the usual Norte/Centro/Lisboa/Alentejo/Algarve/Açores/Madeira divisions (except with a rather outsized notion of Lisboa compared to the usual one), along with a chart of symptom onset dates. For confirmed cases, age and sex, number hospitalized, and symptoms are summarized. The rates of symptoms (translated for your convenience) are:
CoughFeverDifficulty BreathingHeadacheMuscle PainWeakness
65%46%10%37%40%24%

Today is your last chance to fly home to the US from the Schengen area of Europe (i.e., most continental EU countries and some non-EU states with open borders) before Trump's travel ban goes into effect. Forty-eight hours may not sound like much notice compared to the week most closing colleges and universities have given their students to bug out, but it's still generous compared to yesterday's events at CCSU. At 11:00am, in reaction to a student who was a mere contact of a mere suspected case (later proved negative), the President of Connecticut Central State University tossed everyone out immediately. A later update indicates that the residence halls aren't closing until this afternoon (though where the residents were supposed to be in the meantime remains unclear).

New York has opened a drive-through testing facility in New Rochelle which can handle up to 200 cases a day (though perhaps erev Shabbat is not the best time to do so, considering the demographics of that outbreak). The Miami Herald reports that Francis Suarez the mayor of Miami, has tested positive, "four days after the mayor attended a Miami event with a Brazilian government official who later tested positive for the virus." President Bolsonaro was allegedly exposed, and later met with President Trump.

Plague Ships: The Japanese Ministry of Health, Labour, and Welfare reports another case off of Germ Boat #2; one asymptomatic crew member of the Diamond Princess tested positive upon release from quarantine and was sent to hospital. This brings the case count up to 697.

We have a Germ Boat #12, a Viking Cruise Journey riverboat, the RV Bassac Pandaw, with a capacity of 60 passengers. VOA Cambodia reports that one out of five passengers tested positive on Tuesday after Vietnamese authorities alerted Cambodian authorities of a case on their flight from London to Hanoi. Subsequently the remaining 59 passengers [sic] were tested and two more positive cases were found, for a total of three. (The five mentioned in the headline is the total across Cambodia.)

Business Insider reports that Viking Cruises has since suspended operations, and the Washington Post reports (behind a paywall) that Disney has as well. Once again #12 may be the last germ boat, though PlagueBlog suspects otherwise.

Local cancellations: Universal Hub reports that nine local Orthodox Jewish congregations (though that's not nearly all of them) have suspended services starting immediately.

P.S. The President declared a national emergency at a White House presser this afternoon, during which far too many important American health care industry executives (including one from Quest) got far too close to the possibly-exposed President. During questioning he mentioned that Bolsonaro has tested negative (though his wife tested positive), but PlagueBlog doubts the negative result can be relied upon so early on.

P.P.S. Massachusetts' numbers for today are 123 cases (15 over yesterday), with 94 connected to Biogen and 16 not yet connected to Biogen ("under investigation"). The Berkshire cluster and travel numbers are unchanged.

Thursday, March 12, 2020

Day 41: Celebrity Death Pool

The upper echelons of Iranian society were hit "early" on (due to the same people ignoring community spread for weeks on end), but as of yesterday the US is accumulating celebrity cases: Tom Hanks, his wife Rita Wilson (apparently on location in Australia), Utah Jazz player Rudy Gobert (who shut down the NBA single-handedly, possibly by touching all the mics at a presser), a congressional staffer, and a production crew member of Riverdale, a CW TV show. On the other hand, Steve Wozniak's wife turned out to just have a sinus infection after all, and Daniel Radcliffe was also just a rumor.

Kim Jong-un has allegedly fled Pyongyang to avoid infection. In Italy, you can be charged with murder for breaking quarantine. Ravenous wild monkeys with no tourists to feed them are "terrorizing" Lopburi, Thailand.

The Germ Boat count may finally be slowing down. Newsweek reports that Carnival Corporation has suspended all Princess Cruises (operators of Germ Boats #2, #6, #8, and #10) operations for two months. But Carnival is a bigger company than that, with 9 other cruise lines, many of which have already hit the germ boat list: the Holland America Line (#4), AIDA Cruises (#5), Carnival Cruise Line (#7), Costa Cruises (#9), Carnival CSSC, the Cunard Line, the Seabourn Cruise Line, P&O Cruises, and P&O Cruises Australia. Politico reports on the shenanigans of cruise companies in general; PlagueBlog expects more plague ships to come.

Cancellations: Congress has closed the Capitol, House, and Senate to the public. Apparently we have a pro soccer league here in the US, and their season is suspended, too.

P.S. Today's count for Massachusetts is 108, 82 from Biogen, 5 from travel, a cluster of 8 at the Berkshire Medical Center, and 9 still under investigation. Of the 13 new cases, 5 are Biogen-related (thus far). A coronavirus patient who had not travelled was not properly isolated at the Berkshire Medical Center earlier this month, leading to the quarantine of over 50 nurses. The governor has already said we have community spread out there, but the county has only 9 cases total so far so PlagueBlog is unsure what exactly is going on in the Berkshires.

Wednesday, March 11, 2020

Day 40: Mens et Manus

China continues to report low numbers, though they are now experiencing significant importation of cases. Italy has exceeded 10,000 cases, with 631 deaths. Iran has 9,000 cases with 354 deaths, plus 27 deaths from methanol poisoning resulting from a rumored alcohol cure (and, PlagueBlog presumes, a lack of understanding about what sorts of alcohol one should drink). Teheran is now the epicenter of the outbreak, with over 1,800 cases. A second case has been confirmed in Nigeria, in a contact of the first case. In Harare, Zimbabwe, a Thai man fled the hospital to avoid testing.

The US is at 1016 cases with 31 deaths, the latest being a Sacramento County assisted living resident in their 90's. Currently, Washington State leads the nation with 267 cases and 24 deaths. New York, with 173 cases (no deaths), has pulled ahead of California's 109 cases (3 deaths). Massachusetts has the only other large number at 92 cases (though PlagueBlog expects another surge when the DoPH updates again at 4pm). Twelve states and all the territories remain unaffected.

Cancellations: Today's byline is in honor of MIT's closure. Citizenry has a list of college-level closures. Last night, Philadelphia cancelled its St. Patrick's Day parade (via Facebook). DC has "postponed" theirs. Italy, of course, remains closed.

Plague Ships: The saga of Germ Boat #6 floats on: The Mercury News reports that less than half of the passengers had disembarked by last night. Two days apparently only sufficed to remove the ill, Californians, Canadians, and 100 Brits. The fate of the "mostly international" crew is the most in doubt; one plan that's been floated is quarantining them aboard the otherwise empty ship off the coast. The case count for the current cruise as unexpectedly announced by the Vice President was 19 crew and 2 passengers; there seem to have been no updates since then.

Recall that Germ Boat #6 was brought to you by a now-deceased Placer County (CA) man who apparently acquired COVID-19 though community spread, then took the Grand Princess's previous cruise to Mexico (February 11th-21st) on which he infected some fellow passengers and crew. Some of the crew remained aboard for the current cruise to Hawaii, though others moved to other ships, eventually causing the shunning of Germ Boats #8 and #10. The count for the cruise to Mexico is still growing and is now at 14 cases and the one death.

Germ Boat #11 is an unnamed Nile cruise ship quarantined Saturday in Luxor with 45 positive cases (later reduced to 20 after more testing). Once again, the situation was identified through a tourist who returned home after a previous cruise and tested positive there (in this case, a Taiwanese American who returned to Taiwan). Today all remaining foreigners (46 French and American passengers, plus 18 Indians), were released and flown home. Domestic cases may still be quarantined.

P.S. Lawful Masses has an informative video about the Grand Princess lawsuit.

P.P.S. Here on the other germ coast, the Commonwealth of Massachusetts has announced 3 new cases. Also, the CDC has deigned to confirm 5 more of our cases, bringing their total up to 6 out of 95. Biogen cases have increased to 77 out of the 95 (4 more than the new cases for today), so some old cases must have been traced to them.

P.P.P.S. The methanol death count in Iran has risen to 44. Colleges and universities continued to announce closures throughout the day. Also, for a touch of Italy, the governor of New York locked down the New Rochelle cluster with the help of the National Guard.

P.P.P.P.S. There's been some misreporting of Daniele Rugani (Juventus/IT) as the first or second (after Timo Hubers of Hannover 96/DE) soccer player to fall ill. PlagueBlog readers know he's at best the third down; the first soccer player victim was Elham Sheikhi, late of the Iran national women's futsal team.

P.P.P.P.P.S. Italy has closed for business except for pharmacies and grocery stores.

P.P.P.P.P.P.S. There were five new deaths in Washington State. CNN reports that the NBA suspended their season in the middle of a Utah Jazz game tonight, due to an infected player.

Tuesday, March 10, 2020

Day 39: Don't Come Back

Coronavirus cases have now exceeded 116,000, with over 4,000 dead and 64,000 recovered. Italy now leads the non-Chinese pack at over 9,000 cases with 463 dead, and has suspended mortgage payments. Next up is Iran with over 8,000 cases, while South Korea is only slightly above 7,500. Spain is over 1,600, France 1,400, and Germany 1,200. Austria (157 cases) has restricted public gatherings.

For the US, Johns Hopkins calls us at 761 cases now (BNO says 717), with 27 deaths (2 in California, 2 in Florida, and the remainder in Washington State). Testing is ongoing at the Life Care Center of Kirkland, WA, which once had 120 residents (13 to 19 of whom died from coronavirus, depending on who's counting and how recently) but now has less than 60. Of the residents, 31 tested positive, 1 negative, 3 inconclusive, and 20 are pending. Uninfected residents will be moved elsewhere. Apparently there aren't enough test kits for the 65 symptomatic staff members.

The CPAC super-contacter came into contact with but did not infect the President's chief of staff, who is self-quarantining anyway. On the other end of the social spectrum, Fox News reports the city of Detroit is turning the water back on for some non-payers for a $25 fee (possibly waived) and $25 a month, in order to encourage hand washing. PlagueBlog wonders how much the non-payers owe that that plan sounded reasonable to someone, and how it is that people are allowed to live on the books in homes that are unfit for occupancy.

Here in Massachusetts, the gift of the Biogen conference just keeps on giving. If you know where to look, you can get our real case count (41, as of yesterday) broken down by Biogen-did-it, sex, hospitalization status, and county. For those of you unfamiliar with this cesspool of germs the area, Middlesex, Norfolk, and Suffolk County are the Greater Boston area and account for 35 of the cases.) We're currently at 32 Biogen cases, 4 travel-related cases (I'm guessing the one Chinese student and 3 ex Italy), and 5 that they're still investigating (maybe-Biogen-did-it).

On the Plague Ship front, the Straits Times reports on Germ Boat #9, the Costa Fortuna, which successfully docked in Singapore and passengers were allowed off, after having been refused at several Asian ports along their itinerary and having prompted Malaysia to ban cruise ships (apparently due to some healthy Italian passengers). Its next cruise, set to end in Italy, has been cancelled.

Time reports on a new one, Germ Boat #10, another Princess Cruises ship, the Caribbean Princess, also with crew off an infected ship (two of them, presumably off the previous cruise of the Grand Princess, though the papers seem to be having trouble keeping track). The CDC got involved and issued a no-sail order; the passengers are trapped aboard for the moment. The Grand Princess herself (#6) safely docked in Oakland, CA yesterday, though not all passengers disembarked then. Today's news is that passengers are already suing from aboard ship. (PlagueBlog recommends that you disembark from the death trap first, then sue.)

A 24-year-old Vietnamese woman (not to be confused with the jet-setting infected Vietnamese fashion model) returned to Vietnam after being refused testing in London. She tested positive there, becoming Vietnam's "Patient 32". It's not clear she's ex London, though, because she probably caught it from "Patient 17", another Vietnamese visitor to London who had also visited Italy and France (and quite possibly the jet setter or her equally-infected sister).

Local cancellations: Yesterday, Amherst College led the Mass pack by announcing they're going online-only after spring break. (The other four colleges announced plans to keep tabs on the situation, except for UMass Amherst, which says it formed a task force.) Today Harvard joined in. BIDA dances are cancelled through March. Balkan Music Night is also cancelled.

P.S. Channel 10 reports that Dunkies will no longer be refilling reusable coffee cups. PlagueBlog awaits Starbucks' announcement that they'll be creaming your coffee themselves like a real coffee shop, so you don't have to touch the same cream pitcher every other yuppie in town has touched today.

P.P.S. Our governor came home from vacation to declare a state of emergency (or, as PlagueBlog prefers to put it, a Commonwealth of Emergency), perhaps due to our 51 new cases, for a total of 92, 70 from Biogen alone (see this MSN article for details of the dinner and two conferences involved), and 18 untraced. Rhode Island (which is actually a state) and Ohio declared theirs yesterday.

P.P.P.S. The US has hit 1,000 cases, with 30 deaths. The extra deaths are the first New Jersey death, a travel-related case/death in South Dakota, and more deaths in Washington State. Also, MIT has cancelled school for the remainder of the year starting Monday and is sending all students home this coming weekend unless they can prove their home country is more of a basket-case than ours. Facebook and Google have ordered all their North American employees to work from home.

Monday, March 09, 2020

Day 38: Closing Schools Like It's 1918

ABC reports from the governor's mouth that New York State has jumped to 142 cases, 19 in the eponymous city. Kansas has reported its first case today. Connecticut reported its first case yesterday, apparently ex California. Washington State has stealthily reported 3 more deaths in their ever-increasing case counts, bringing the US to 22 deaths among 551 cases.

A JAMA paper from 2007 has been making the Internet rounds lately, Nonpharmaceutical Interventions Implemented by US Cities During the 1918-1919 Influenza Pandemic. The interventions were school closings, isolation/quarantine (isolation for the actually ill, and quarantining of their contacts), and banning of public gatherings:
Public gathering bans typically meant the closure of saloons, public entertainment venues, sporting events, and indoor gatherings were banned or moved outdoors; outdoor gatherings were not always canceled during this period (eg, Liberty bond parades); there were no recorded bans on shopping in grocery and drug stores.
While people were still susceptible to flu after (or during) these interventions, they did have some benefits, namely,
[...]delaying the temporal effect of a pandemic; reducing the overall and peak attack rate; and reducing the number of cumulative deaths. Such measures could potentially provide valuable time for production and distribution of pandemic-strain vaccine and antiviral medication. Optimally, appropriate implementation of nonpharmaceutical interventions would decrease the burden on health care services and critical infrastructure.
It's a good read, but the tl;dr conclusion is:
These findings contrast with the conventional wisdom that the 1918 pandemic rapidly spread through each community killing everyone in its path. Although these urban communities had neither effective vaccines nor antivirals, cities that were able to organize and execute a suite of classic public health interventions before the pandemic swept fully through the city appeared to have an associated mitigated epidemic experience.
It would be nice if we learned from the past, but we seem to forget instead. New York City was a model of public health promptness a hundred years ago, while Boston took a long time to react and suffered for it (see Table 1). Nevertheless, a few Massachusetts schools have closed for the moment: The Stratton School in Arlington was closed by the city due to a Biogen parent's symptomatic kid.

Individual schools in Boston, Malden, Plainville, Plymouth, Wellesley, and Worcester have closed for Friday or Monday, often for far less reason (e.g., in Worcester it's a contact of a relative of a staffer) in conjunction with a wiping-down-the-school effort and a planned reopening after the scrub. This is hardly a unified public health intervention. At least Boston University is planning for remote learning, though in an abundance-of-caution way rather than a do-it-yesterday way.

Education Week has a map of coronavirus-related school closures, though several recent Massachusetts cases seem to be misreported at ongoing closures rather than cleaning days. (Wellesley has already reopened.) New York and New Jersey have several district closures. In Seattle, whose response time wasn't too bad in 1918, many schools have already reopened.

Cancellations: Never mind those scrub-by-night school cancellations; NEFFA has been cancelled.

P.S. The New York Post reports the head of the Port Authority was among today’s cases. Though he’s been in contact with the governor, he’s not getting tested.

P.P.S. Five more deaths, four in Washington and one through community spread in Santa Clara County, California, have brought the US death count to 27. Santa Clara County has cancelled "mass" gatherings (of a thousand people) for three weeks. Italy has banned gatherings and restricted movement across the country.

P.P.P.S. Following in Ireland's footsteps, Boston has cancelled our St. Patrick's Day parade. Chicago has not.

Sunday, March 08, 2020

Day 37: The Band Plays On

The Associated Press reports on our elderly presidential contenders campaigning on, including a quote from a Bernie Sis who thinks coronavirus is just "to distract people." In other news, Oregon has declared a state of emergency, presumably to distract people, and Twitter reports two more retroactive deaths at the Life Care Center of Kirkland, WA. The total case count for the US is 475.

Massachusetts insurers will be fully covering coronavirus testing, but then they're used to paying for the weird stuff. YMMV if you live elsewhere in the US. It's a good thing, too, because our Department of Public Health has announced 15 new presumptive cases (all from Biogen's battiness), increasing our count to 28 (with 23 directly linked to Biogen).

New Jersey is up to 6 cases. Vermont announced its first case yesterday. The New York Times now has a US case map.

The US State Department joins PlagueBlog in recommending against cruise ship travel. Though their purview is international travel, their advice is surprisingly unqualified:
U.S. citizens, particularly travelers with underlying health conditions, should not travel by cruise ship.
Speaking of plague ships, Germ Boat #8, the Regal Princess, is currently pacing back and forth off South Florida after being refused docking in Fort Lauderdale pending testing of two crew members formerly of Germ Boat #6, the Grand Princess.

Israel (with a case count of 39, only one untraced) is quarantining all arrivals, while Micronesia has closed its borders completely. France has banned public gatherings of more than 1,000 people, except for protests. (It's unclear whether this is a civil rights exception or a final solution to France's protest problems.)

Day 36 Retrospective

Day 36 (yesterday) was an exciting day for the Northeast and US Germ Boats. New York’s caseload jumped to 76, prompting the governor to declare a state of emergency. Acela service between NYC and DC was cancelled until late May. Bloomberg reports bad times for our lobster industry, what with the bottom falling out of the Asian giant edible spider import market.

The Commonwealth of Massachusetts now has our own tracker, which still lists yesterday’s stats of 13 cases. An infectious disease conference in Boston (CROI) was moved online, because apparently not everyone in the biotech sector here is completely insane.

Vice President Pence accidentally announced 21 confirmed cases aboard Germ Boat #6, the Grand Princess. Also, a Germ Boat #7 was christened when a “medical matter” (that is, a suspected coronavirus case) trapped passengers aboard the Carnival Panorama in Long Beach, CA, until a negative test result could be obtained. (The following cruise was shortened by one day.) PlagueBlog recommends against taking cruises at this (or any) time. At least one more death has been recorded for #2, the Diamond Princess, as well, bringing the official total to 7.

Another LAX screener was diagnosed. The US hit 19 deaths and Brazil hit 17 cases (two in Rio). MasterCard closed its offices in NYC and São Paulo due to a coronaviral connection between the two. The SXSW conference that several tech companies pulled out of earlier in the week has been cancelled.

A relatively new Chinese hotel in Quanzhou housing quarantined case contacts collapsed, killing at least 10. The Pope started streaming to keep crowds from gathering to see him, and the Vatican confirmed its first case.

Poland’s sixth case apparently caught it from the first case on a bus. The leader of the Italian Democratic Party fell ill. A cluster of 60 cases in Spain was linked to a funeral. The Netherlands reported their first death and a total of 182 cases.

Friday, March 06, 2020

Day 35: 100,000 Strong

Today the worldwide case count hit 100,000, with over 55,000 recovered and almost 3,400 dead. PlagueBlog will be at an inadvisable public gathering on the NH/MA border this weekend and will be unable to provide our usual level of gory detail. Just one note: Biogen maintains that its three infected employees are all out of state, even though they seem to have infected one another here in Massachusetts, meaning that the ex Italy case in their county is not an employee. PlagueBlog reserves judgement for the moment.

One other point of information: you may have heard about two strains, L and S, one nastier than the other, of SARS-Cov-2. The paper the media picked this up from is pretty baseless and has already been debunked in the literature, so ignore.

P.S. Channel 4 reports 3 Massachusetts cases from Biogen’s what-were-you-thinking conference last week, and 2 more out-of-state cases.

Thursday, March 05, 2020

Day 34: Ex Boston

Channel 5 reports that we may have exported coronavirus to Tennessee in the person of a Williamson County (TN) man who flew from Nashville to Logan and back. Channel 10 reports he came to Boston for an international meeting "at Biogen" in Cambridge [reddit speculates this meeting was actually at the Boston Marriott Copley Square in the heart of Boston] last week, from which attendees took home both flu and COVID-19 (three positives so far). Our third Massachusetts case, also in Middlesex County (location of both Cambridge and yours truly) has been reported by the state as ex Italy but by NBC as ex Biogen, is awaiting confirmation by the CDC. PlagueBlog would like to thank you now for reading, because posting may come to an abrupt and possibly permanent halt at any time now.

Boston.com reports that the wayward New Hampshire medical worker "is now complying" with quarantine after exposing a bunch of Dartmouth Tuck Business School students at a mixer. One Tuck student "estimated that about a hundred business school students attended, along with 30 or 40 resident physicians associated with Dartmouth-Hitchcock, an academic medical center located near Dartmouth College."

In other local news, Governor Cuomo tweets that there are 5 new confirmed cases in New Rochelle, a couple in their 40's with three children who were friends of the previous family. There are also two untraced cases in New York City. New Jersey has two presumptive cases.

Texas has three new cases, two of them in Harris County (i.e., Houston). California is lousy with cases, but a notable one is one of the medical screeners from LAX. The CDC state-by-state map is updating daily again, possibly due to agitation from reddit. In less official but more accurate news-based counting, the US is up to 221 cases and 12 deaths.

An eight-month-old baby is a new Australian case, ex Iran. South Africa's first case is ex Italy.

On the bright side, the Diamond Princess has been downgraded to 696 cases and 6 deaths, due to some double-counting of cases.

P.S. Germ Boat #6 is another Princess Cruises ship, the Grand Princess. The story is similar to that of previous Germ Boats: passengers on a prior cruise later tested positive (including one death; these are some of the California mainland cases), so the current passengers have been condemned to a slow death by quarantine off the coast near San Francisco. Test kits are being flown in by helicopter.

Wednesday, March 04, 2020

Day 33: Biden Our Time

Iran has leapt ahead of Italy, with 2,922 cases (including 23 members of parliament) and 92 deaths. The Ayatollah was seen wearing gloves. Germany and France have each exceeded 200 cases and Spain is not far behind. Case counts are rising across Europe, with notable jumps in the UK, Switzerland, Norway, and the Netherlands. Portugal now has five cases (the fifth ex Italy, and the third and fourth connected to the initial two). Poland, famed for its resistance to the Black Death, has reported its first case.

Here in the New World, Canada is up to 33 cases, with several new cases ex Iran, while Mexico is holding at 5 and Brazil at 2. (The low case count in South America is the only thing between us and the WHO declaring this a pandemic.) The US has reached 132 cases, with 9 deaths (all in Washington State). CNN is tracking cases state-by-state. Most of today's new cases are in California and associated with travel, though at least one is untraced.

Governor Cuomo announced that many suspected New York State cases, including those in Buffalo and Oneida, tested negative. On the downside, the 50-year-old Westchester County case managed to super-spread the virus to his wife, a son (20), a daughter (14), and a neighbor. The children's schools (including Yeshiva University) will be closed today. He also announced that SUNY/CUNY students studying abroad in certain countries will be flown home and quarantined.

Tuesday, March 03, 2020

Day 32: Don't Lick the Shrine

The official case count is now over 92,000 cases. While Italy has exceeded 2,000 cases and South Korea 5,000, Iran (2,336) continues to be the most infectious, with almost as many new cases per day (835 today) as South Korea and the only significant death rate (11 today) outside of China (33 today). Notable figures in society continue to fall ill; the head of emergency services is now a confirmed case, and Mohammad Mirmohammadi, member of the Expediency Council and advisor to Khamenei, reportedly died of COVID-19 yesterday. The situation in Iran may have something to do with the government's failure to keep people from licking shrines—or, more likely, the very fact that they needed to tell people not to lick shrines in the first place. PlagueBlog also recommends you don't lick the shrine.

Back on the home front, Boston.com reports some more details about the first Rhode Island case, a school administrator. The second official case is one of the students from that trip to Italy. The article mentions that another chaperone is a suspected case; this suspected case may be Massachusetts' second case, a 27-year-old Cohasset woman who was on the same school trip. Whether a Massachusetts school was involved is still unclear.

Two cases have been confirmed in New York state. The first, a 39-year-old NYC health care worker, was ex Iran, but the second one is suspected local, untraced transmission to a Westchester County man in his 50's over whom not one but two local schools have already closed. Governor Kemp of Georgia reported two confirmed cases there ex Italy.

An unspecified foreigner in his 30's is the 706th case confirmed (yesterday) aboard the Diamond Princess. It's apparently a crew member, not the food blogger, who has escaped confinement (though not Japan) and is still food blogging while waiting to be readmitted to the US.

In non-humanitarian news, a stowaway cat at the port of Chennai is facing deportation over coronavirus fears. PETA India is concerned about its fate if returned to China and has offered to adopt it out.

Cancellations: The Louvre apparently remained closed today, though whether solely through worker action or now officially is unclear. The Japanese government is planning to cancel the annual Fukushima Memorial. The Chicago Tribune reports a major local trade show cancellation as well as other cancellations and postponements across the country. Twitter, Facebook, and Intel have pulled out of the SXSW conference in Austin.

P.S. The AP reports three new deaths in Washington State. Two seem to be posthumous confirmation of deaths from last week, and the third may be yet another nursing home resident from the Life Care Center of Kirkland, WA.

P.P.S. There's a second case in New Hampshire, a close contact of the first patient, though apparently not a result of the first patient breaking quarantine on Friday to attend a social event.

Monday, March 02, 2020

Day 31: The Accusations Fly

The official case count is over 89,000 cases, with over 3,000 dead and over 45,000 recovered. PlagueBlog cannot vouch for the Chinese number, which exceeds 80,000 cases with 2,912 deaths. South Korea now has 4,335 cases with 26 deaths. Iran has surged to 1,501 cases with 66 deaths. Italy is still slightly ahead at 1,696 cases and 34 deaths. Germany has hit 150 cases, France 130, and Spain 120.

Portugal has finally reported cases, both males in Porto, though only one is ex Spain. The 60-year-old doctor vacationed in Italy, while the 33-year-old construction worker worked in Spain and had some connection to Valência. Scotland has also reported its first case, ex Italy.

The US now has 88 cases, but no new deaths since yesterday. CNBC and MSN report on doctors' and suspected patients' lack of access to COVID-19 tests, despite CDC claims to the contrary. The New York Times also links CDC testing restrictions to weeks of covert spread of the virus in the Pacific Northwest. In other news, the CDC once again accidentally released an infected quarantined evacuee in San Antonio, but the patient was quickly recaptured.

The Bangkok Post reports that Thailand's first death, a 35-year-old sales clerk who dealt with Chinese tourists and passed away on Saturday, did not actually have an underlying condition; his dengue fever was a misdiagnosis and his only known disease was COVID-19. He had been in hospital since January 27th, stopped testing positive for coronavirus on February 16th, and succumbed to multiple-organ failure on February 29th.

And lastly, a cool toy: Genomic epidemiology of novel coronavirus (HCoV-19)

P.S. Steve Wozniak theorizes on Twitter that he was the American Patient Zero.

P.P.S. The Washington State cluster has now brought the US death count to 6.

P.P.P.S. New Hampshire has confirmed a case, in a hospital employee, ex Italy. Rumor has it he's been working since he returned from Italy. The nationwide case count is up to 100 as of 9pm EST.

Sunday, March 01, 2020

Day 30: Looking Fully Incubated Now

NBC News reports that yesterday's death in Washington State turned out to be not just a domestic case, but also another unsourced infection in a non-traveller. In more disturbing news (from the same source), the CDC is responding to "the first possible outbreak" in a long-term care facility, the Life Care Center of Kirkland, WA.

In local news, the first Rhode Island "presumptive" case has been confirmed, a man in his 40's who'd travelled to Italy in February. Forty of his contacts are being monitored and/or quarantined at home by the RI Department of Health, but the patient himself is in an undisclosed hospital "nearby".

The US stands at 73 cases with one death. Canada has 20 cases. Mexico has 4, the fourth is ex Italy. Italy has jumped to 1,694 cases, though only 34 deaths. Unfortunate neighbors Germany and France are at or above 100 cases. Spain is at 76, the UK at 35, and Sweden, Austria, Switzerland, and the Netherlands have at least 10 cases each.

Iran reported 11 new deaths today, bringing their total to 978 cases with 54 deaths. Kuwait and Bahrain are now in the 40's, although Bahrain has only a quarter the population of Singapore.

South Korea has 3,736 with 21 deaths. Japan has 241 cases with 5 deaths. Hong Kong and Singapore have at least 100 cases each. Thailand, currently at 42 cases, has reported their first death.

P.S. PlagueBlog neglected to mention a canine case identified on Thursday: a pet Pomeranian in Hong Kong tested positive for the disease after her owner, Yvonne Chow Hau Yee, fell ill. The dog initially showed no symptoms; PlagueBlog has been unable to find any updates on its disease status, but Hong Kong is now quarantining pets.

P.P.S. New York has reported a case, and Washington State a second death.

P.P.P.S. Another Washington State case is a postal worker. PlagueBlog will refrain from "going postal" puns.